Multiplex proteomics for prediction of major cardiovascular events in type 2 diabetes
نویسندگان
چکیده
منابع مشابه
Recurrence of Cardiovascular Events in Patients With Type 2 Diabetes
OBJECTIVE The purpose of this study was to assess incidence of and risk factors for recurrent cardiovascular disease (CVD) in type 2 diabetes. RESEARCH DESIGN AND METHODS We estimated the incidence of recurrent cardiovascular events in type 2 diabetic patients, aged 40-97 years, followed by a network of diabetes clinics. The analysis was conducted separately for 2,788 patients with CVD at enr...
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M e t h o d s Design: Randomized placebo-controlled trial (Collaborative Atorvastatin Diabetes Study [CARDS]). Allocation: Concealed.* Blinding: Blinded (clinicians, patients, pharmacists, data collectors, outcome assessors, monitoring committee, and data analysts).* Follow-up period: Median 3.9 years. Setting: 132 clinical centers in the United Kingdom and Ireland. Patients: 2838 patients 40 t...
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Review of: Neal B, Perkovic V, Mahaffey K, et al. Canagliflozin and cardiovascular and renal events in type 2 diabetes. N Engl J Med. 2017;377:644-657. The report combines the data from two trials, CANVAS and CANVAS-Renal, which were designed to evaluate the safety and effect of canagliflozin, an SGLT-2 inhibitor, on the appearance of cardiovascular and renal events in patients with type 2 diab...
متن کاملRisk Prediction of Cardiovascular Disease in Type 2 Diabetes
OBJECTIVE Risk prediction models obtained in samples from the general population do not perform well in type 2 diabetic patients. Recently, 5-year risk estimates were proposed as being more accurate than 10-year risk estimates. This study presents a diabetes-specific equation for estimation of the absolute 5-year risk of first incident fatal/nonfatal cardiovascular disease (CVD) in type 2 diabe...
متن کاملPlasma Lipidomic Profiles Improve on Traditional Risk Factors for the Prediction of Cardiovascular Events in Type 2 Diabetes Mellitus.
BACKGROUND Clinical lipid measurements do not show the full complexity of the altered lipid metabolism associated with diabetes mellitus or cardiovascular disease. Lipidomics enables the assessment of hundreds of lipid species as potential markers for disease risk. METHODS Plasma lipid species (310) were measured by a targeted lipidomic analysis with liquid chromatography electrospray ionizat...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2018
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-018-4641-z